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Antigenic Specificity | Docking Protein 1 (DOK1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | DOK1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr/abl), a chimeric protein whose presence is associated with CML. DOK1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. DOK2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling. |
Immunogen | KLH-conjugated synthetic peptide between 9-39 amino acids from the N-terminal region of human DOK1. |
Other Names | docking protein 1, 62kDa (downstream of tyrosine kinase 1), DOK1, MGC117395, MGC138860, P62DOK, Downstream of tyrosine kinase 1, p62(dok), pp62, p62 (dok), docking protein 1, docking protein 1, docking protein 1 , docking protein 1 , 62kDa (downstream of tyrosine kinase 1), 62kDa (downstream of tyrosine kinase 1), 62kDa (downstream of tyrosine kinase 1) , 62kDa (downstream of tyrosine kinase 1) , DOK1, DOK1, DOK1 , DOK1 , MGC117395, MGC117395, MGC117395 , MGC117395 , MGC138860, MGC138860, MGC138860 , MGC138860 , P62DOK, P62DOK, P62DOK , P62DOK , Downstream of tyrosine kinase 1, Downstream of tyrosine kinase 1, Downstream of tyrosine kinase 1 , Downstream of tyrosine kinase 1 , p62(dok), p62(dok), p62(dok) , p62(dok) , pp62, pp62, pp62 , pp62 , p62 (dok), p62 (dok), p62 (dok) , p62 (dok) |
Gene, Accession # | UniProt: Q99704 |
Catalog # | abx033622 |
Price | please inquire |
Order / More Info | Docking Protein 1 (DOK1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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