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Antigenic Specificity | Androgen Receptor (AR) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100 µg, |
Concentration | 2 mg/ml |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Androgen Receptor (AR) antibody is a Rabbit polyclonal antibody for the detection of androgen receptor. The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract from the normal 9-34 repeats to the pathogenic 38-62 repeats causes spinal bulbar muscular atrophy (SBMA, also known as Kennedy's disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Alternative splicing results in multiple transcript variants encoding different isoforms. |
Immunogen | androgen receptor |
Other Names | ANDR, Androgen receptor, DHTR, Dihydrotestosterone receptor, NR3C4, AR, AIS, AR8, HUMARA, HYSP1, KD, SBMA, SMAX1, TFM, RP11-383C12.1, Nuclear Receptor Subfamily 3,Group C,Member 4, Testicular Feminization, Kennedy Disease, ANDR, ANDR, ANDR , ANDR , Androgen receptor, Androgen receptor, Androgen receptor , Androgen receptor , DHTR, DHTR, DHTR , DHTR , Dihydrotestosterone receptor, Dihydrotestosterone receptor, Dihydrotestosterone receptor , Dihydrotestosterone receptor , NR3C4, NR3C4, NR3C4 , NR3C4 , AR, AR, AR , AR , AIS, AIS, AIS , AIS , AR8, AR8, AR8 , AR8 , HUMARA, HUMARA, HUMARA , HUMARA , HYSP1, HYSP1, HYSP1 , HYSP1 , KD, KD, KD , KD , SBMA, SBMA, SBMA , SBMA , SMAX1, SMAX1, SMAX1 , SMAX1 , TFM, TFM, TFM , TFM , RP11-383C12.1, RP11-383C12.1, RP11-383C12.1 , RP11-383C12.1 , Nuclear Receptor Subfamily 3,Group C,Member 4, Nuclear Receptor Subfamily 3,Group C,Member 4, Nuclear Receptor Subfamily 3,Group C,Member 4 , Nuclear Receptor Subfamily 3,Group C,Member 4 , Testi |
Gene, Accession # | AR, Gene ID: 367, UniProt: P10275 |
Catalog # | abx011629 |
Price | please inquire |
Order / More Info | Androgen Receptor (AR) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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