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Antigenic Specificity | Beclin 1 (BECN1) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | Protein A purified |
Size | 100 µg, |
Concentration | 2 mg/ml |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Beclin 1 (BECN1) antibody is a Mouse monoclonal antibody for the detection of Beclin 1. Beclin-1 (BECN1), also known as ATG6 or VPS30, has a central role in autophagy, a process of programmed cell survival, which is increased during periods of cell stress and extinguished during the cell cycle. Beclin-1, may play a role in antiviral host defense. It protects against infection by a neurovirulent strain of Sindbis virus. Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. A progressively reduced Beclin-1 expression is reported to correlate with the primary tumor growth of squamous cell carcinoma and adenocarcinoma of the lung. Caspase-mediated cleavage of Beclin 1 promotes crosstalk between apoptosis and autophagy. |
Immunogen | beclin 1, autophagy related |
Other Names | APG6, ATG 6, ATG6, ATG6 autophagy related 6 homolog, Bcl-2-interacting protein beclin, Beclin 1 (coiled coil moesin like BCL2 interacting protein), Beclin 1 autophagy related, Beclin-1, Beclin1, BECN 1, BECN1, beclin 1, autophagy related, VPS30, GT197, Protein GT197, Coiled-coil myosin-like BCL2-interacting protein, APG6, APG6, APG6 , APG6 , ATG 6, ATG 6, ATG 6 , ATG 6 , ATG6, ATG6, ATG6 , ATG6 , ATG6 autophagy related 6 homolog, ATG6 autophagy related 6 homolog, ATG6 autophagy related 6 homolog , ATG6 autophagy related 6 homolog , Bcl-2-interacting protein beclin, Bcl-2-interacting protein beclin, Bcl-2-interacting protein beclin , Bcl-2-interacting protein beclin , Beclin 1 (coiled coil moesin like BCL2 interacting protein), Beclin 1 (coiled coil moesin like BCL2 interacting protein), Beclin 1 (coiled coil moesin like BCL2 interacting protein) , Beclin 1 (coiled coil moesin like BCL2 interacting protein) , Beclin 1 autophagy related, Beclin 1 autophagy related, Beclin 1 autoph |
Gene, Accession # | BECN1, Gene ID: 8678, UniProt: Q14457 |
Catalog # | abx240266 |
Price | please inquire |
Order / More Info | Beclin 1 (BECN1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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