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Antigenic Specificity | Calsenilin (KCNIP3) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | Protein G purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | KChIP3 is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This protein is also shown to function as a calcium-regulated transcriptional repressor, and to interact with presenilins. Mutations in the presenilin genes have been implicated in Alzheimer's disease. Due to utilization of an alternate in-frame translation start codon, the gene for this protein encodes two isoforms with different sizes. |
Immunogen | KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human KChIP3. |
Other Names | KCNIP3, CSEN, DREAM, KCHIP3, Calsenilin, A-type potassium channel modulatory protein 3, DRE-antagonist modulator, Kv channel-interacting protein 3, KCNIP3, KCNIP3, KCNIP3 , KCNIP3 , CSEN, CSEN, CSEN , CSEN , DREAM, DREAM, DREAM , DREAM , KCHIP3, KCHIP3, KCHIP3 , KCHIP3 , Calsenilin, Calsenilin, Calsenilin , Calsenilin , A-type potassium channel modulatory protein 3, A-type potassium channel modulatory protein 3, A-type potassium channel modulatory protein 3 , A-type potassium channel modulatory protein 3 , DRE-antagonist modulator, DRE-antagonist modulator, DRE-antagonist modulator , DRE-antagonist modulator , Kv channel-interacting protein 3, Kv channel-interacting protein 3, Kv channel-interacting protein 3 , Kv channel-interacting protein 3 |
Gene, Accession # | UniProt: Q9Y2W7 |
Catalog # | abx028515 |
Price | please inquire |
Order / More Info | Calsenilin (KCNIP3) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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