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Antigenic Specificity | Killer Cell Immunoglobulin Like Receptor 2DL3 (KIR2DL3) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | KIR2DL3 antibody is a Rabbit polyclonal antibody against KIR2DL3. Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several ""framework"" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq, Jul 2008]. |
Immunogen | Recombinant protein of human KIR2DL3. |
Other Names | Killer cell immunoglobulin-like receptor 2DL3, CD158 antigen-like family member B2, KIR-023GB, Killer inhibitory receptor cl 2-3, MHC class I NK cell receptor, NKAT2a, KIR2DL3, CD158B2, KIRCL23, NKAT2, killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3, CD158b, GL183, KIR-K7b, KIR-K7c, MGC129943, NKAT, NKAT2B, p58, 2 Domains Long Cytoplasmic Tail 3, Killer cell immunoglobulin-like receptor 2DL3, Killer cell immunoglobulin-like receptor 2DL3, Killer cell immunoglobulin-like receptor 2DL3 , Killer cell immunoglobulin-like receptor 2DL3 , CD158 antigen-like family member B2, CD158 antigen-like family member B2, CD158 antigen-like family member B2 , CD158 antigen-like family member B2 , KIR-023GB, KIR-023GB, KIR-023GB , KIR-023GB , Killer inhibitory receptor cl 2-3, Killer inhibitory receptor cl 2-3, Killer inhibitory receptor cl 2-3 , Killer inhibitory receptor cl 2-3 , MHC class I NK cell receptor, MHC class I NK cell receptor, MHC class I NK cell recept |
Gene, Accession # | KIR2DL3, Gene ID: 3804, UniProt: P43628 |
Catalog # | abx001423 |
Price | please inquire |
Order / More Info | Killer Cell Immunoglobulin Like Receptor 2DL3 (KIR2DL3) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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