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Antigenic Specificity | IL6 (Siltuximab biosimilar) |
Clone | monoclonal |
Host Species | Chimeric Human/Mouse |
Reactive Species | human |
Isotype | IgG1 kappa |
Format | Protein A/G purified |
Size | 100 µg, 1 mg, |
Concentration | typically between 0.5-2.0 mg/ml. |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Siltuximab is a monoclonal antibody biosimilar expressed in CHO cells, targeting IL6, for use in laboratory research applications. This product is not suitable for use as medicines or in human, therapeutic or diagnostic applications. Siltuximab is a chimeric (human-mouse) monoclonal immunoglobulin G1-kappa antibody produced in a Chinese hamster ovary (CHO) cell line by recombinant DNA technology. Siltuximab prevents the binding of IL-6 to soluble and membrane-bound IL-6 receptors by forming high affinity complexes with human interleukin-6 (IL-6). Its use is indicated for the treatment of adult patients with multicentric Castleman's disease (MCD) who are human immunodeficiency virus (HIV) negative and human herpesvirus-8 (HHV-8) negative. MCD is a rare blood disorder caused by dysregulated IL-6 production, proliferation of lymphocytes, and subsequent enlargement of the lymph nodes. It is administered as a 1 hour intravenous infusion every 3 weeks. |
Immunogen | n/a |
Other Names | Siltuximab, IL6, 541502-14-1 |
Gene, Accession # | CAS: 541502-14-1 |
Catalog # | abx831169 |
Price | please inquire |
Order / More Info | IL6 (Siltuximab biosimilar) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
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Telephone: +1 832 327 7413
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Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950