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Antigenic Specificity | Vascular Endothelial Growth Factor A (VEGFA) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | Protein A purified |
Size | 100 µg, |
Concentration | 2 mg/ml |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Vascular Endothelial Growth Factor A (VEGFA) antibody is a Mouse monoclonal antibody for the detection of VEGF. VEGFA, also named as VEGF or VPF, belongs to the PDGF/VEGF growth factor family. It is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. VEGFA induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. Defects in VEGFA are a cause of susceptibility to microvascular complications of diabetes type 1 (MVCD1). VEGFA has 13 isoforms with MW 16kd to 45kd. Some isoforms has homodimer form, such as VEGFA189 (38kd), VEFGA110 (34kd). VEGFA is a 34kd to 42kd, dimeric, disulfide-bound glycoprotein. VEGF-A exists in at least seven homodimeric isoforms. The monomers consist of 121, 145, 148, 165, 183, 189, or 206 amino acids (PMID:15602010). This antibody can recognize all the isoforms of VEFGA. |
Immunogen | vascular endothelial growth factor A |
Other Names | VEGF, Vascular endothelial growth factor A, VEGF-A, Vascular permeability factor, VPF, VEGF, VEGF, VEGF , VEGF , Vascular endothelial growth factor A, Vascular endothelial growth factor A, Vascular endothelial growth factor A , Vascular endothelial growth factor A , VEGF-A, VEGF-A, VEGF-A , VEGF-A , Vascular permeability factor, Vascular permeability factor, Vascular permeability factor , Vascular permeability factor , VPF, VPF, VPF , VPF |
Gene, Accession # | Gene ID: 7422, UniProt: P15692 |
Catalog # | abx239935 |
Price | please inquire |
Order / More Info | Vascular Endothelial Growth Factor A (VEGFA) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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