CHEK1 (pS280) Antibody from ABBEXA LTD
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| Antigenic Specificity | CHEK1 (pS280) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 20 µl, 50 µl, 100 µl, 200 µl |
| Concentration | > 0.5 mg/ml |
| Applications | WB, IHC, IF/ICC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CHEK1 (pS280) Antibody is a Rabbit Polyclonal antibody against CHEK1 (pS280). The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene. |
| Immunogen | Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding S280 of human CHEK1. |
| Other Names | CHEK1, CHK1 checkpoint homolog (S. pombe), CHK1, CHK1 checkpoint homolog, Checkpoint, S. pombe, homolog of, 1, Serine/threonine-protein kinase Chk1, Cell cycle checkpoint kinase, Checkpoint kinase-1, CHEK1, CHEK1, CHEK1, CHEK1, CHK1 checkpoint homolog (S. pombe), CHK1 checkpoint homolog (S. pombe), CHK1 checkpoint homolog (S. pombe), CHK1 checkpoint homolog (S. pombe), CHK1, CHK1, CHK1, CHK1, CHK1 checkpoint homolog, CHK1 checkpoint homolog, CHK1 checkpoint homolog, CHK1 checkpoint homolog, Checkpoint, S. pombe, homolog of, 1, Checkpoint, S. pombe, homolog of, 1, Checkpoint, S. pombe, homolog of, 1, Checkpoint, S. pombe, homolog of, 1, Serine/threonine-protein kinase Chk1, Serine/threonine-protein kinase Chk1, Serine/threonine-protein kinase Chk1, Serine/threonine-protein kinase Chk1, Cell cycle checkpoint kinase, Cell cycle checkpoint kinase, Cell cycle checkpoint kinase, Cell cycle checkpoint kinase, Checkpoint kinase-1, Checkpoint kinase-1, Checkpoint kinase-1, Checkpoint kinase-1 |
| Gene, Accession # | CHEK1, Gene ID: 1111, UniProt: O14757 |
| Catalog # | abx000106 |
| Price | please inquire |
| Order / More Info | CHEK1 (pS280) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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