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Antigenic Specificity | Protein DJ-1 (DJ-1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Park 7 acts as positive regulator of androgen receptor-dependent transcription, and may function as redox-sensitive chaperone and as sensor for oxidative stress, as well as preventing aggregation of SNCA. This protein has been shown to protect neurons against oxidative stress and cell death, and to play a role in fertilization. Park7 is detected in tau inclusions in brains from neurodegenerative disease patients, and is generally highly expressed in pancreas, kidney, skeletal muscle, liver, testis and heart, with detectable levels in placenta, brain, astrocytes, Sertoli cells, spermatogonia, spermatids and spermatozoa. Defects in Park7 are the cause of autosomal recessive early-onset Parkinson disease 7 (PARK7), a form of Parkinson disease characterized by onset before 40 years, slow progression and initial good response to levodopa. |
Immunogen | KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DJ-1. |
Other Names | DJ-1, ONCOGENE DJ1, PARK7 AMYOTROPHIC LATERAL SCLEROSIS-PARKINSONISM/DEMENTIA COMPLEX 2, PARK7 GENE, PARK7, Protein DJ-1, Parkinson disease protein 7, DJ-1, DJ-1, DJ-1 , DJ-1 , ONCOGENE DJ1, ONCOGENE DJ1, ONCOGENE DJ1 , ONCOGENE DJ1 , PARK7 AMYOTROPHIC LATERAL SCLEROSIS-PARKINSONISM/DEMENTIA COMPLEX 2, PARK7 AMYOTROPHIC LATERAL SCLEROSIS-PARKINSONISM/DEMENTIA COMPLEX 2, PARK7 AMYOTROPHIC LATERAL SCLEROSIS-PARKINSONISM/DEMENTIA COMPLEX 2 , PARK7 AMYOTROPHIC LATERAL SCLEROSIS-PARKINSONISM/DEMENTIA COMPLEX 2 , PARK7 GENE, PARK7 GENE, PARK7 GENE , PARK7 GENE , PARK7, PARK7, PARK7 , PARK7 , Protein DJ-1, Protein DJ-1, Protein DJ-1 , Protein DJ-1 , Parkinson disease protein 7, Parkinson disease protein 7, Parkinson disease protein 7 , Parkinson disease protein 7 |
Gene, Accession # | UniProt: Q99497 |
Catalog # | abx032825 |
Price | please inquire |
Order / More Info | Protein DJ-1 (DJ-1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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