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Antigenic Specificity | Coagulation Factor VIII (F8) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | F8 antibody is a Rabbit polyclonal antibody against F8. This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq, Jul 2008]. |
Immunogen | Recombinant protein of human F8. |
Other Names | AHF, F8B, F8C, HEMA, FVIII, DXS1253E, Coagulation factor VIII, Antihemophilic factor, Procoagulant component, F8, AHF, AHF, AHF , AHF , F8B, F8B, F8B , F8B , F8C, F8C, F8C , F8C , HEMA, HEMA, HEMA , HEMA , FVIII, FVIII, FVIII , FVIII , DXS1253E, DXS1253E, DXS1253E , DXS1253E , Coagulation factor VIII, Coagulation factor VIII, Coagulation factor VIII , Coagulation factor VIII , Antihemophilic factor, Antihemophilic factor, Antihemophilic factor , Antihemophilic factor , Procoagulant component, Procoagulant component, Procoagulant component , Procoagulant component , F8, F8, F8 , F8 |
Gene, Accession # | F8, Gene ID: 2157, UniProt: P00451 |
Catalog # | abx001205 |
Price | please inquire |
Order / More Info | Coagulation Factor VIII (F8) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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