Cyclin-Dependent-Like Kinase 5 (CDK5) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Cyclin-Dependent-Like Kinase 5 (CDK5) antibody, protein, ELISA kits.
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| Antigenic Specificity | Cyclin-Dependent-Like Kinase 5 (CDK5) |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human, rat, monkey |
| Isotype | IgG1 |
| Format | ascites |
| Size | 100 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CDK5 is a protein kinase of the CDK family. Unlike other members of this family, it is not activated by cyclins but by p35 (CDK5R1) and p39. An important regulator of neuronal positioning during brain development. May also play a role in synaptogenesis and neurotransmission. Substrates include TAU, MAP2, NF-H and -M, Nudel, PDE6, beta catenin, amphyphysin, dynamin I, synapsin 1, Munc-18, and NMDA receptor 2A. Plays a role in myogenesis, haematopoietic cell differentiation, spermatogenesis, insulin secretion, and lens differentiation. Implicated in the pathology of neurofibrillary tangles and formation of senile plaques, hallmarks of AlzheimerOs disease. Induces tau phosphorylation and aggregation and neurofibrillary tangle deposition and neurodegeneration in in vitro and in vivo animal models. Brain samples from AlzeimerOs pateints show elevated CDK5 activity. |
| Immunogen | Purified recombinant fragment of human CDK5 expressed in E. Coli. |
| Other Names | CDK5, CRK6, Cell division protein kinase 5, PSSALRE, TAU protein kinase II catalytic subunit, TPKII catalytic subunit, kinase Cdk5, Serine/threonine-protein kinase PSSALRE, CDKN5, Tau protein kinase II catalytic subunit;TPKII catalytic subunit, CDK5, CDK5, CDK5 , CDK5 , CRK6, CRK6, CRK6 , CRK6 , Cell division protein kinase 5, Cell division protein kinase 5, Cell division protein kinase 5 , Cell division protein kinase 5 , PSSALRE, PSSALRE, PSSALRE , PSSALRE , TAU protein kinase II catalytic subunit, TAU protein kinase II catalytic subunit, TAU protein kinase II catalytic subunit , TAU protein kinase II catalytic subunit , TPKII catalytic subunit, TPKII catalytic subunit, TPKII catalytic subunit , TPKII catalytic subunit , kinase Cdk5, kinase Cdk5, kinase Cdk5 , kinase Cdk5 , Serine/threonine-protein kinase PSSALRE, Serine/threonine-protein kinase PSSALRE, Serine/threonine-protein kinase PSSALRE , Serine/threonine-protein kinase PSSALRE , CDKN5, CDKN5, CDKN5 , CDKN5 , Tau prot |
| Gene, Accession # | Gene ID: 1020, UniProt: Q00535 |
| Catalog # | abx010546 |
| Price | please inquire |
| Order / More Info | Cyclin-Dependent-Like Kinase 5 (CDK5) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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