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Antigenic Specificity | Poly(RC) Binding Protein 2 (PCBP2) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IHC, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PCBP2 antibody is a Rabbit polyclonal antibody against PCBP2. The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. Thsi gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. |
Immunogen | Recombinant protein of human PCBP2. |
Other Names | HNRPE2, MGC110998, hnRNP-E2, PCBP2, HNRPE2, HNRPE2, HNRPE2 , HNRPE2 , MGC110998, MGC110998, MGC110998 , MGC110998 , hnRNP-E2, hnRNP-E2, hnRNP-E2 , hnRNP-E2 , PCBP2, PCBP2, PCBP2 , PCBP2 |
Gene, Accession # | PCBP2, Gene ID: 5094, UniProt: Q15366 |
Catalog # | abx001971 |
Price | please inquire |
Order / More Info | Poly(RC) Binding Protein 2 (PCBP2) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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