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Antigenic Specificity | Myelin Basic Protein (MBP) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | ascites |
Size | 100 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The classic group of MBP isoforms (isoforms 4-14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non- classic group of MBP isoforms (isoforms 1-3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T- cells and neural cells. Differential splicing events combined to optional posttranslational modifications give a wide spectrum of isomers, each of them having maybe a specialized function. |
Immunogen | Recombinant fusion protein with Maltose binding protein tag. |
Other Names | Maltose Binding Protein, MBP, MBP Tag, Myelin basic protein, Myelin A1 protein, Myelin membrane encephalitogenic protein, MGC99675, Maltose Binding Protein, Maltose Binding Protein, Maltose Binding Protein , Maltose Binding Protein , MBP, MBP, MBP , MBP , MBP Tag, MBP Tag, MBP Tag , MBP Tag , Myelin basic protein, Myelin basic protein, Myelin basic protein , Myelin basic protein , Myelin A1 protein, Myelin A1 protein, Myelin A1 protein , Myelin A1 protein , Myelin membrane encephalitogenic protein, Myelin membrane encephalitogenic protein, Myelin membrane encephalitogenic protein , Myelin membrane encephalitogenic protein , MGC99675, MGC99675, MGC99675 , MGC99675 , general, human, mouse, rat, rabbit, pig, goat, sheep, chicken, monkey, fish, guinea pig, dog, cow, horse |
Gene, Accession # | MBP, Gene ID: 4155, UniProt: P02686 |
Catalog # | abx011639 |
Price | please inquire |
Order / More Info | Myelin Basic Protein (MBP) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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