Edit |   |
---|---|
Antigenic Specificity | Interferon Gamma (IFNG) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein G purified |
Size | 100 µl, |
Concentration | 1 mg/ml |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Interferon gamma (IFN gamma) is a pro-inflammatory cytokine that is central in host resistance to infection. It is mainly produced by natural killer cells and CD4+ and CD8+ T cells, its receptors are found on nearly all cells, where it activates diverse responses that enable potential host cells to prevent invasive infection by bacteria, parasites and viruses. Takayanagi et al. (2000) demonstrated that IFN gamma strongly suppresses osteoclastogenesis by interfering with the RANKL (602642)-RANK (603499) signaling pathway. Tsubota et al. (1999) reported that this upregulation in Sjogren syndrome patients may be controlled by interferon gamma through the activation of transcription factor NFKB. |
Immunogen | Purified recombinant fragment of human IFN-gamma expressed in E. Coli. |
Other Names | IFG, IFI, IFNG, IFN gamma, IFN-gamma (Interferon gamma) Human, Human Ifn-Gamma, MAB TO HUMAN IFN-GAMMA, Interferon Gamma, MAB TO INTERFERON GAMMA, IFN-, IFG, IFG, IFG , IFG , IFI, IFI, IFI , IFI , IFNG, IFNG, IFNG , IFNG , IFN gamma, IFN gamma, IFN gamma , IFN gamma , IFN-gamma (Interferon gamma) Human, IFN-gamma (Interferon gamma) Human, IFN-gamma (Interferon gamma) Human , IFN-gamma (Interferon gamma) Human , Human Ifn-Gamma, Human Ifn-Gamma, Human Ifn-Gamma , Human Ifn-Gamma , MAB TO HUMAN IFN-GAMMA, MAB TO HUMAN IFN-GAMMA, MAB TO HUMAN IFN-GAMMA , MAB TO HUMAN IFN-GAMMA , Interferon Gamma, Interferon Gamma, Interferon Gamma , Interferon Gamma , MAB TO INTERFERON GAMMA, MAB TO INTERFERON GAMMA, MAB TO INTERFERON GAMMA , MAB TO INTERFERON GAMMA , IFN-, IFN-, IFN- , IFN- |
Gene, Accession # | IFNG, Gene ID: 3458, UniProt: P01579 |
Catalog # | abx011002 |
Price | please inquire |
Order / More Info | Interferon Gamma (IFNG) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950