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Antigenic Specificity | Apolipoprotein B (ApoB) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | ascites |
Size | 100 µl, |
Concentration | n/a |
Applications | ELISA, WB, IF/ICC, FCM |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypo beta lipoproteinemia, normotriglyceridemic hypo beta lipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. |
Immunogen | Purified recombinant fragment of human ApoB expressed in E. Coli. |
Other Names | APOB, apolipoprotein B (including Ag(x) antigen), FLDB, apoB-100, apoB-48, apolipoprotein B, apolipoprotein B48, Apolipoprotein B-100, Apo B-100, Apo B-48, LDLCQ4, LDB, APOB, APOB, APOB , APOB , apolipoprotein B (including Ag(x) antigen), apolipoprotein B (including Ag(x) antigen), apolipoprotein B (including Ag(x) antigen) , apolipoprotein B (including Ag(x) antigen) , FLDB, FLDB, FLDB , FLDB , apoB-100, apoB-100, apoB-100 , apoB-100 , apoB-48, apoB-48, apoB-48 , apoB-48 , apolipoprotein B, apolipoprotein B, apolipoprotein B , apolipoprotein B , apolipoprotein B48, apolipoprotein B48, apolipoprotein B48 , apolipoprotein B48 , Apolipoprotein B-100, Apolipoprotein B-100, Apolipoprotein B-100 , Apolipoprotein B-100 , Apo B-100, Apo B-100, Apo B-100 , Apo B-100 , Apo B-48, Apo B-48, Apo B-48 , Apo B-48 , LDLCQ4, LDLCQ4, LDLCQ4 , LDLCQ4 , LDB, LDB, LDB , LDB |
Gene, Accession # | APOB, Gene ID: 338, UniProt: P04114 |
Catalog # | abx012218 |
Price | please inquire |
Order / More Info | Apolipoprotein B (ApoB) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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