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Antigenic Specificity | CHK1 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1 |
Format | Protein G purified |
Size | 100 µl |
Concentration | 1 mg/ml |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CHK1, also known as CHEK1, it is a kinase that phosphorylates cdc25, an important phosphatase in cell cycle control, particularly for entry into mitosis.Cdc25, when phosphorylated on serine 216 by CHK1 becomes bound by an adaptor protein in the cytoplasm.Therefore it is inhibited from removing the inhibiting phosphate from MPF (mitotic/maturation promoting factor) added by Wee1.Consequently, a cell is prevented from entering mitosis.CHK1 can also phosphorylate p53 at Ser20 in vitro. |
Immunogen | Purified recombinant fragment of CHK1 expressed in E. coli. |
Other Names | Checkpoint, S. pombe, homolog of, 1, CHEK1, CHK1, CHK1 checkpoint homolog (S. pombe), Serine/threonine-protein kinase Chk1, kinase Chk1, CHK1 checkpoint homolog, Cell cycle checkpoint kinase, Checkpoint kinase-1, Checkpoint, Checkpoint, Checkpoint, Checkpoint, S. pombe, S. pombe, S. pombe, S. pombe, homolog of, homolog of, homolog of, homolog of, 1, 1, 1, 1, CHEK1, CHEK1, CHEK1, CHEK1, CHK1, CHK1, CHK1, CHK1, CHK1 checkpoint homolog (S. pombe), CHK1 checkpoint homolog (S. pombe), CHK1 checkpoint homolog (S. pombe), CHK1 checkpoint homolog (S. pombe), Serine/threonine-protein kinase Chk1, Serine/threonine-protein kinase Chk1, Serine/threonine-protein kinase Chk1, Serine/threonine-protein kinase Chk1, kinase Chk1, kinase Chk1, kinase Chk1, kinase Chk1, CHK1 checkpoint homolog, CHK1 checkpoint homolog, CHK1 checkpoint homolog, CHK1 checkpoint homolog, Cell cycle checkpoint kinase, Cell cycle checkpoint kinase, Cell cycle checkpoint kinase, Cell cycle checkpoint kinase, Checkpoint kinase-1, Checkpoint kinase-1, Checkpoint kinase-1, Checkpoint kinase-1 |
Gene, Accession # | Gene ID: 1111 |
Catalog # | abx015730 |
Price | please inquire |
Order / More Info | CHK1 Antibody from ABBEXA LTD |
Product Specific References | n/a |
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