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Antigenic Specificity | Potassium Voltage-Gated Channel Subfamily J Member 11 (KCNJ11) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, FCM |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ATP-sensitive potassium (K (ATP)) channels are found in endocrine cells, neurons and both smooth and striated muscle, where they play an important role in controlling insulin secretion and vascular tone, and protect neurons under metabolic stress. Kir6.2 is a member of the inward rectifier potassium channel family, which is characterised by a greater tendency to allow potassium flow into the cell rather than out of it. It associates with the sulphonylurea receptor SUR1/ABCC8 to form a subfamily of K (ATP) channels that, when mutated or misregulated, are associated with forms of hyperinsulinemic hypoglycemia, neonatal diabetes, or pre-disposition to type 2 diabetes mellitus. |
Immunogen | KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human KCNJ11. |
Other Names | ATP-sensitive inward rectifier potassium channel 11, IKATP, Inward rectifier K(+) channel Kir6.2, Potassium channel, inwardly rectifying subfamily J member 11, KCNJ11, BIR, HHF2, PHHI, TNDM3, KIR6.2, Inward rectifier K (+) channel Kir6.2, potassium inwardly-rectifying channel, subfamily J, member 11, MGC133230, ATP-sensitive inward rectifier potassium channel 11, ATP-sensitive inward rectifier potassium channel 11, ATP-sensitive inward rectifier potassium channel 11 , ATP-sensitive inward rectifier potassium channel 11 , IKATP, IKATP, IKATP , IKATP , Inward rectifier K(+) channel Kir6.2, Inward rectifier K(+) channel Kir6.2, Inward rectifier K(+) channel Kir6.2 , Inward rectifier K(+) channel Kir6.2 , Potassium channel, Potassium channel, Potassium channel , Potassium channel , inwardly rectifying subfamily J member 11, inwardly rectifying subfamily J member 11, inwardly rectifying subfamily J member 11 , inwardly rectifying subfamily J member 11 , KCNJ11, KCNJ11, KCNJ11 , KCNJ11 |
Gene, Accession # | UniProt: Q14654 |
Catalog # | abx034279 |
Price | please inquire |
Order / More Info | Potassium Voltage-Gated Channel Subfamily J Member 11 (KCNJ11) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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