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Antigenic Specificity | EpCAM |
Clone | rEGP40-1372 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 kappa |
Format | unconjugated |
Size | 20 µg |
Concentration | 200 µg/mL |
Applications | Immunohistochemistry, Staining Methods, Western Blotting |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | EGP40 is a 40-43kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma. Target Information: This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]. |
Immunogen | Recombinant human EpCAM protein fragment from extracellular domain (around aa77-202) (exact sequence is proprietary) |
Other Names | DIAR5|EGP-2|EGP314|EGP40|ESA|HNPCC8|KS14|KSA|M4S1|MIC18|MK-1|TACSTD1|TROP1|adenocarcinoma-associated antigen|cell surface glycoprotein Trop-1|epithelial glycoprotein 314|human epithelial glycoprotein-2|major gastrointestinal tumor-associated protein GA733-2|membrane component|chromosome 4|surface marker (35kD glycoprotein)|tumor-associated calcium signal transducer 1|epithelial cell adhesion molecule|EPCAM|ECS-1|ECS1|ESA1|M17S1|Flotillin 2 (epidermal surface antigen 1)|epidermal surface antigen|flotillin-2|membrane component chromosome 17 surface marker 1|chromosome 17|surface marker 1 (35kD protein identified by monoclonal antibody ECS-1)|flotillin 2|FLOT2|EGP|Ep-CAM|epithelial glycoprotein|sb:cb6|tacstd|wu:fj17g02|zgc:110304|zgc:77119|pan-epithelial glycoprotein|tumor-associated calcium signal transducer|MGC80540|epithelial cell adhesion molecule S homeolog|epcam.S|cd326|hegp-2|co17-1a|ga733-2|EpCAM1|Ly74|Tacsd1|gp40|Trop-1 protein|lymphocyte antigen 74|mEGP314|panepithelial glycoprotein 314|protein 289A |
Gene, Accession # | Gene ID: 4072 |
Catalog # | ABIN6934069 |
Price | $274 |
Order / More Info | EpCAM Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |