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Antigenic Specificity | CD5 |
Clone | OX-19 |
Host Species | Mouse |
Reactive Species | rat |
Isotype | IgG1 |
Format | fluorescein (FITC) conjugate |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | anti-rat CD5 monoclonal antibody recognizes a determinant expressed on all rat thymocytes and peripheral T lymphocytes. It has been determined that there are 15,000 antigenic sites for ABIN133208per cell on thymocytes and 30,000 on peripheral T cells. This antibody does not bind to B cells, macrophages, NK cells or mast cells (2). Also, no cross- reactivity has been detected with non-lymphoid cells in intestine, thymus, spleen or lymph node (2). The antigen recognized by ABIN133208is a surface glycoprotein of Mr 69,000 (2), and is most likely the homologue of the mouse Ly 1 and human CD5 antigen. The antigen has also been shown to have an important functional role in T cell activation and differentiation indicating a use for this antibody in related studies. The antibody may be employed to label cells with anti-mouse Ig conjugated to fluorescein, peroxidase or 125I and has been successfully used in labelling of cryostat sections (3). Target Information: May act as a receptor in regulating T-cell proliferation. |
Immunogen | Rat thymocyte glycoproteins, depleted of LC-A, W3/13 antigen and Thy 1. . Fusion Partner: P3-NSI-I-Ag4(NS1/1) . Immunocyte Donor: BALB/c spleen |
Other Names | LEU1|T1|CD5 antigen (p56-62)|T-cell surface glycoprotein CD5|lymphocyte antigen T1Leu-1|CD5 molecule|CD5|Ly-1|Ly-12|Ly-A|Lyt-1|lymphocyte antigen 1|CD5 antigen|Lymphocyte antigen CD5|CD74 antigen|invariant polypeptide of major|lymphocyte receptor CD5|t-cell surface glycoprotein CD5-like|CD5 molecule like|CD5L |
Gene, Accession # | Gene ID: 54236 |
Catalog # | ABIN133208 |
Price | $280 |
Order / More Info | CD5 Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |