RAS Antibody from ANTIBODIES-ONLINE GmbH
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| Antigenic Specificity | RAS |
| Clone | 11F2 |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat, zebrafish |
| Isotype | IgG |
| Format | unconjugated |
| Size | 100 µL |
| Concentration | 1 µg/µL |
| Applications | Flow Cytometry, Western Blotting |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Ras superfamily is a protein superfamily of small GTPases, which are all related, to a degree, to the Ras protein subfamily (the key human members of which are KRAS, NRAS, and HRAS). Receptor tyrosine kinases and G protein-coupled receptors activate Ras, which then stimulates the Raf-MEK-MAPK pathway. GTPase-activating proteins (GAP) normally facilitate the inactivation of Ras. However, research studies have shown that in 30% of human tumors, point mutations in Ras prevent the GAP-mediated inhibition of this pathway. The most common oncogenic Ras mutation found in tumors is Gly12 to Asp12 (G12D), which prevents Ras inactivation, possibly by increasing the overall rigidity of the protein. This antibody is predicted to react with H-Ras, N-Ras and K-Ras. |
| Immunogen | Human Ras aa 1-100 |
| Other Names | RAB1B|RAS|fb53a02|oncogene|si:zc101n13.3|wu:fb53a02|ras-related protein Rab-1A|RAB1A, member RAS oncogene family b|rab1ab|asr|resistance to audiogenic seizures |
| Gene, Accession # | Gene ID: 19412, 368883 |
| Catalog # | ABIN6944747 |
| Price | $490 |
| Order / More Info | RAS Antibody from ANTIBODIES-ONLINE GmbH |
| Product Specific References | n/a |
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
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