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Antigenic Specificity | Ly6g |
Clone | RB6-8C5 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2b kappa |
Format | PE-Cy7 conjugate |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The RB6-8C5 antibody binds to mouse Ly-6G, commonly known as Gr-1, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Gr-1 is differentially expressed during development and maturation of cells in the myeloid lineage and is expression at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils. In the mouse, the RB6-8C5 antibody is typically used in combination with the macrophage labeling antibody M1/70 (Anti-CD11b) for phe- notypic analysis of monocytes, macrophages and granulocytes.Note: The RB6-8C5 antibody has been reported to cross-react with Ly-6C on cells expressing this antigen (Fleming et al. 1993. J. Immunol. 151:2399-2408 and Sasmono et al. 2007. J. Leukoc. Biol. 82: 111-123) and has been cited in the literature for identification of Ly-6G/Ly-6C. Other reports suggest that this antibody is specific for Ly-6G, without cross-reactivity for Ly-6C (Nagendra S. and Schlueter AJ. 2003. cytometry A, 58(2): 195-200). |
Immunogen | n/a |
Other Names | Gr-1|Gr1|Ly-6G|ly-6G.1|lymphocyte antigen 6G|lymphocyte antigen 6 complex, locus G|Ly6g |
Gene, Accession # | Gene ID: 546644 |
Catalog # | ABIN7278431 |
Price | $166 |
Order / More Info | Ly6g Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |