APOA5 Antibody from ANTIBODIES-ONLINE GmbH
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| Antigenic Specificity | APOA5 |
| Clone | 2G1H11 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 100 µL |
| Concentration | n/a |
| Applications | ELISA, Immunocytochemistry, Western Blotting |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Description: Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglycerides, whereas a knock-in model with human ApoA5 produced 50-70% lower concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor- agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Despite these compelling molecular biology data, relatively little is known about ApoA5 protein in human serum. This antibody pair detected recombinant apoa5 protein in sandwich ELISA format and could be potential reagents for the development of clinical diagnostic kits. Aliases: RAP3, APOAV, APOA-V, MGC126836, MGC126838 Target Information: The protein encoded by this gene is an apolipoprotein that plays an important role in regulating the plasma triglyceride levels, a major risk factor for coronary artery disease. It is a component of high density lipoprotein and is highly similar to a rat protein that is upregulated in response to liver injury. Mutations in this gene have been associated with hypertriglyceridemia and hyperlipoproteinemia type 5. This gene is located proximal to the apolipoprotein gene cluster on chromosome 11q23. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Oct 2009]. |
| Immunogen | Purified recombinant fragment of human Apoa5 expressed in E. coli. |
| Other Names | APOAV|RAP3|apo-AV|apolipoprotein A5|regeneration-associated protein 3|APOA5|Apolipoprotein A-V|1300007O05Rik|apoA-V|MGC140487|apolipoprotein AV|apolipoprotein A5 L homeolog|apoa5.L |
| Gene, Accession # | Gene ID: 116519 |
| Catalog # | ABIN1724647 |
| Price | $727 |
| Order / More Info | APOA5 Antibody from ANTIBODIES-ONLINE GmbH |
| Product Specific References | n/a |
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
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