VWF Antibody from ANTIBODIES-ONLINE GmbH
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| Antigenic Specificity | VWF |
| Clone | VWF-1465 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 kappa |
| Format | unconjugated |
| Size | 100 µg |
| Concentration | 200 µg/mL |
| Applications | Immunohistochemistry, Staining Methods, Western Blotting |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi's sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen. Target Information: The glycoprotein encoded by this gene functions as both an antihemophilic factor carrier and a platelet-vessel wall mediator in the blood coagulation system. It is crucial to the hemostasis process. Mutations in this gene or deficiencies in this protein result in von Willebrand's disease. An unprocessed pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008]. |
| Immunogen | Recombinant fragment of human vWF protein (aa1815-1939) (exact sequence is proprietary) |
| Other Names | si:ch1073-474e24.1|von Willebrand factor|vwf|F8VWF|VWD|coagulation factor VIII VWF|6820430P06Rik|AI551257|B130011O06Rik|C630030D09 |
| Gene, Accession # | Gene ID: 7450 |
| Catalog # | ABIN6940895 |
| Price | $575 |
| Order / More Info | VWF Antibody from ANTIBODIES-ONLINE GmbH |
| Product Specific References | n/a |
ANTIBODIES-ONLINE GmbH
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