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Antigenic Specificity | Dendritic Cells |
Clone | OX-62 |
Host Species | Mouse |
Reactive Species | rat |
Isotype | IgG1 |
Format | fluorescein (FITC) conjugate |
Size | 100 µg |
Concentration | 0.1 mg/ml |
Applications | Flow Cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ABIN133165 (OX-62) monoclonal antibody was raised against density gradient-enriched rat veiled (dendritic) cells obtained from lymph. This antibody only labeled cells characteristic of veiled cells the antigen recognized by ABIN133165 is expressed at low to moderate levels by a subset of spleen, thymus and bone marrow dendritic cells. In lymphoid tissues, the labeling correlated with dendritic cells (DC), however in skin, MHC Class II cells were ABIN133165 , while other CD3 cells with dendritic morphology were strongly stained with ABIN133165. Therefore, it seems that this antibody may be restricted to DC and probably T cells. (This has since been contradicted by the fact that the CD3 cells with dendritic morphology were confirmed to stain negative for ABIN133204 (OX-19), and are therefore not T cells.) The ABIN133165 antigen has the biochemical characteristics of an integrin (ABIN133165 recognizes the -like subunit) as determined by SDS-PAGE. This monoclonal antibody is useful for cell purification, delineating lineage relationships among cells with dendritic morphology and for molecular studies. The OX-62 antigen is not essential for T cell activation. The ABIN133165 clone has been use in flow cytometry, immunohistochemistry, immunoprecipitation and cell surface radioiodination. |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | ABIN133418 |
Price | $280 |
Order / More Info | Dendritic Cells Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |