Human CD86 Antibody from BIOLEGEND

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Antigenic SpecificityHuman CD86
CloneIT2.2
Host SpeciesMouse
Reactive Specieshuman, cynomolgus, rhesus
IsotypeIgG2b, kappa
FormatPE-Fire™ 700 conjugate
Size25 tests
Concentrationn/a
ApplicationsFC - Quality tested
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DescriptionPE/Fire™ 700 anti-human CD86. CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells.
Immunogenn/a
Other NamesB7-2, B70
Gene, Accession #Gene ID: 942
Catalog #305463
Price$176
Order / More InfoHuman CD86 Antibody from BIOLEGEND
Product Specific Referencesn/a
BIOLEGEND
BIOLEGEND
BIOLEGEND
8999 BioLegend Way
San Diego CA 92121
P: (858) 455-9588
P: 1-877-Bio-Legend (246-5343)
F: (858) 455-9587

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