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Antigenic Specificity | CD95 (Fas) |
Clone | A16086F |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b, κ |
Format | purified, low endotoxin, azide-free |
Size | 1 mg |
Concentration | n/a |
Applications | Block |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Ultra-LEAF™ Purified anti-CD95 (Fas). FAS was initially purified and cloned from SKW6.4 cells and a cDNA library of human T cell lymphoma KT-3 cells. FAS is a type I transmembrane protein and belongs to the TNF receptor superfamily. The extracellular region of the FAS possesses three cystein-rich domains characteristic of the TNF superfamily, and the intracellular region includes a death domain (DD). The binding of FASL to FAS induces conformational changes in FAS, leading to recruitment of FADD and procaspase-8, and assembly of th |
Immunogen | Recombinant human FAS |
Other Names | Tumor necrosis factor receptor superfamily member 6 (TNFRSF6), ALPS1A, APO-1, Apoptosis antigen 1 (APT1), CD95, FAS1, FASTM, FS-7-associated surface antigen |
Gene, Accession # | Gene ID: 355 |
Catalog # | 684402 |
Price | $715 |
Order / More Info | CD95 (Fas) Antibody from BIOLEGEND |
Product Specific References | n/a |