Edit |   |
---|---|
Antigenic Specificity | Human CD141 (Thrombomodulin) |
Clone | M80 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | PE-Dazzle™ 594 conjugate |
Size | 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PE/Dazzle™ 594 anti-human CD141 (Thrombomodulin). CD141 is a 75 kD, single chain, type I membrane glycoprotein also known as thrombomodulin, TM, THRM, THBD, and fetomodulin. CD141 is an important cofactor in the protein C anticoagulant system. After binding to its ligand thrombin, CD141 activates protein C, which degrades clotting factors Va and VIIIa, and as a consequence the amount of thrombin is reduced. CD141 is expressed on macrophages, monocytes, a subpopulation of myeloid dendritic cells, vascular endothelial cells, and keratinocytes. Be |
Immunogen | n/a |
Other Names | Thrombomodulin, TM, THRM, THBD, Fetomodulin, BDCA-3 |
Gene, Accession # | Gene ID: 7056 |
Catalog # | 344120 |
Price | $382 |
Order / More Info | Human CD141 (Thrombomodulin) Antibody from BIOLEGEND |
Product Specific References | n/a |