Mouse CD317 (BST2, PDCA-1) Antibody from BIOLEGEND

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Antigenic SpecificityMouse CD317 (BST2, PDCA-1)
Clone927
Host SpeciesRat
Reactive Speciesmouse
IsotypeIgG2b, kappa
FormatSpark PLUS UV395™ conjugate
Size100 µg
Concentrationn/a
ApplicationsFC - Quality tested
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DescriptionSpark PLUS UV395™ anti-mouse CD317 (BST2, PDCA-1). CD317, known as BST2, tetherin, HM1.2 antigen, bone marrow stromal antigen 2, or PDCA-1, is type II transmembrane glycoprotein with a molecular mass of 29-33 kD. It is predominantly expressed on Type I IFN-producing cells (IPCs) in naïve mice, but is up-regulated on most cell types following stimulation with type I IFNs and IFN-gamma. It is highly expressed on terminally differentiated normal plasmacytoid dendritic cells and some tumor cells, such as multiple myeloma, renal cell carcinoma, and melanoma cells. BST2 is a recently identified, IFN-induced cellular response factor that blocks release of HIV-1 and other retroviruses from infected cells. BST2 has been found to be the natural ligand of ILT7 in human model.
ImmunogenMouse plasmacytoid dendritic cells (DCs)
Other NamesBST2, tetherin, HM1.2 antigen, bone marrow stromal antigen 2, PDCA-1
Gene, Accession #Gene ID: 69550
Catalog #127048
Price$330
Order / More InfoMouse CD317 (BST2, PDCA-1) Antibody from BIOLEGEND
Product Specific Referencesn/a
BIOLEGEND
BIOLEGEND
BIOLEGEND
8999 BioLegend Way
San Diego CA 92121
P: (858) 455-9588
P: 1-877-Bio-Legend (246-5343)
F: (858) 455-9587

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