Edit |   |
---|---|
Antigenic Specificity | Human CD152 (CTLA-4) |
Clone | L3D10 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | APC-Fire™ 750 conjugate |
Size | 100 tests |
Concentration | n/a |
Applications | Intracellular Staining for Flow Cytometry (ICFC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | APC/Fire™ 750 anti-human CD152 (CTLA-4). CD152, also known as Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4), is a 33 kD member of the immunoglobulin superfamily. It is transiently expressed on activated T cells. CTLA4 is expressed on the surface of helper T cells and transmits an inhibitory signal to T cells. Regulatory T cells express high levels of CTLA-4. CTLA-4 (CD152) is similar to CD28 in amino acid sequence, structure, and genomic organization. Whereas CD28 delivers a costimulatory signal in T cell activation, CTLA-4 negatively regu |
Immunogen | Extracellular domain of human CTLA-4 and human IgG1 Fc fusion protein |
Other Names | Cytotoxic T-Lymphocyte Antigen 4 |
Gene, Accession # | Gene ID: 1493 |
Catalog # | 349930 |
Price | $364 |
Order / More Info | Human CD152 (CTLA-4) Antibody from BIOLEGEND |
Product Specific References | n/a |