Edit |   |
---|---|
Antigenic Specificity | Human CD45 Recombinant |
Clone | QA19A35 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | Spark Violet™ 423 conjugate |
Size | 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Spark Violet™ 423 anti-human CD45 Recombinant. CD45 is a 180-240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes and platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. |
Immunogen | n/a |
Other Names | LCA, T200 |
Gene, Accession # | Gene ID: 5788 |
Catalog # | 311804 |
Price | $370 |
Order / More Info | Human CD45 Recombinant Antibody from BIOLEGEND |
Product Specific References | n/a |