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Antigenic Specificity | c-Fos Phospho (Ser32) |
Clone | A22009C |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB), ICC, Intracellular Staining for Flow Cytometry (ICFC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-c-Fos Phospho (Ser32). The proto-oncogene c-Fos is the human homolog of the retroviral v-Fos oncogene, and is a member of the Fos family of transcription factors. c-Fos forms heterodimers with proteins of the Jun family of transcription factors to form the Activator Protein-1 complex (AP-1). This complex is involved in critical cellular processes such as inflammation, cell proliferation, differentiation, survival, hypoxia, bone development and angiogenesis which suggests c-Fos is an important therapeutic target for cancer, vascular remodeling, acute inflammation and autoimmune diseases. In addition, increases in c-Fos expression and activation are associated with neuronal activity induced by psychoactive drugs. Expression of c-Fos is rapid and transitory, and phosphorylation at residues Ser32 and Thr232 by Erk5 increases protein stability and nuclear localization. |
Immunogen | Synthetic peptide from human c-Fos phosphorylated at Ser32. |
Other Names | G0S7, p55, cFos, c-Fos, Proto-oncogene, Transcription Factor subunit, AP-1 |
Gene, Accession # | Gene ID: 2353 |
Catalog # | 631252 |
Price | $455 |
Order / More Info | c-Fos Phospho (Ser32) Antibody from BIOLEGEND |
Product Specific References | n/a |