Edit |   |
---|---|
Antigenic Specificity | Bax |
Clone | 2D2 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB), IP, IHC-P, ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-Bax. Bax is a 21 kD pro-apoptotic protein known to regulate apoptosis. Bax is found in the cytoplasm, mitochondria, and nucleus and is highly expressed in hematopoietic stem cells, ovaries, and lymph nodes. Bax binds the anti-apoptotic protein Bcl-2 as a heterodimer or forms homodimers. The relative levels of pro-apoptotic proteins such as Bax and anti-apoptotic proteins such as Bcl-2 determines whether cell death will occur following an apoptotic stimulus. Bax accelerates the opening of mitochondria |
Immunogen | Amino acids 3-16 of human Bax protein |
Other Names | BCL2 associated X protein, apoptosis regulator Bax |
Gene, Accession # | Gene ID: 581 |
Catalog # | 633602 |
Price | $218 |
Order / More Info | Bax Antibody from BIOLEGEND |
Product Specific References | PubMed: 28549559, 28690187, 28690187, 28549559, 32124934, 33000263, 32582999 |