Edit |   |
---|---|
Antigenic Specificity | AGR2 |
Clone | W19087A |
Host Species | Rat |
Reactive Species | human |
Isotype | IgG2a, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB), ICC, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-AGR2. AGR2 is a disulfide isomerase that catalyzes protein folding and thiol-disulfide exchange reactions in the ER lumen. It can also serve as a chaperone for secretory proteins, and is essential for maturation of cysteine-rich transmembrane receptors, including the intestinal glycoprotein mucin. In addition to its role in ER homeostasis, AGR2 can also exert pro-oncogenic function. In many tumors, AGR2 is overexpressed and secreted into the tumor microenvironment, where it disrupts epithelial cell to |
Immunogen | Partial recombinant human AGR2 protein |
Other Names | Anterior Gradient 2, Protein Disulphide Isomerase Family Member, HAG-2, PDIA17, XAG-2, HPC8, Epididymis Secretory Protein Li 116, Secreted Cement Gland Homolog, GOB-4, HEL-S-116 |
Gene, Accession # | Gene ID: 10551 |
Catalog # | 943102 |
Price | $293 |
Order / More Info | AGR2 Antibody from BIOLEGEND |
Product Specific References | n/a |