PTEN Antibody from BIOLEGEND

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Antigenic SpecificityPTEN
Clone4C11A11
Host SpeciesMouse
Reactive Specieshuman, mouse
IsotypeIgG2b, κ
Formatpurified
Size100 µg
Concentrationn/a
ApplicationsWestern Blot (WB), ICC
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DescriptionPurified anti-PTEN. PTEN was discovered as a tumor suppressor with lipid and protein phosphatase activity. Heterozygous loss of PTEN in mice contribute to the development of a variety of types of cancer, suggesting that insufficient PTEN activity results in increased cancer susceptibility. PTEN negatively regulates the PI3K/AKT pathway by dephosphorylating the second messenger phosphoinositide 3,4,5-triphosphate (PIP3) produced by phosphoinositide 3-kinase (PI3K), which results in inhibition of abnormal cell prolif
ImmunogenPartial human PTEN recombinant protein (303-403aa)
Other NamesMMAC1, BZS, TEP1, MHAM1, GLM2, PTEN1
Gene, Accession #Gene ID: 5728
Catalog #655002
Price$265
Order / More InfoPTEN Antibody from BIOLEGEND
Product Specific ReferencesPubMed: 30736829, 32736533
BIOLEGEND
BIOLEGEND
BIOLEGEND
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P: (858) 455-9588
P: 1-877-Bio-Legend (246-5343)
F: (858) 455-9587

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