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Antigenic Specificity | Mouse CD117 (c-Kit) |
Clone | W19361A |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a, κ |
Format | purified, low endotoxin, azide-free |
Size | 100 µg |
Concentration | n/a |
Applications | Block |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Ultra-LEAF™ Purified anti-mouse CD117 (c-Kit). CD117 is a 145 kD protein tyrosine kinase also known as c-Kit and stem cell factor receptor (SCFR). It belongs to the CSF-1/PDGF receptor subfamily. CD117 is a receptor for stem cell factor (SCF) or c-Kit ligand. CD117 is expressed on pluripotent hematopoietic progenitor cells, mast cells, and acute myeloid leukemia cells (AML). c-Kit ligand binding of CD117 induces dimerization and phosphorylation of CD117, and activates the downstream signaling, including PI3K, JAK/STAT, PLC-γ and MAPK pathway |
Immunogen | Recombinant mouse CD117 (c-Kit) |
Other Names | Mast/stem cell growth factor receptor Kit, SCFR, c-Kit, Kit, CD117 |
Gene, Accession # | Gene ID: 16590 |
Catalog # | 946803 |
Price | $171 |
Order / More Info | Mouse CD117 (c-Kit) Antibody from BIOLEGEND |
Product Specific References | n/a |