Edit |   |
---|---|
Antigenic Specificity | Human CD261 (DR4, TRAIL-R1) |
Clone | DJR1 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | TotalSeq™-B oligomer conjugate |
Size | 10 µg |
Concentration | n/a |
Applications | PG |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TotalSeq™-B1183 anti-human CD261 (DR4, TRAIL-R1). DR4 is 56 kD member 10A of the TNFR superfamily (TNFRSF10A), also known as TRAIL-R1, Apo-2, and CD261. It is expressed at low levels by activated T cells and some tumors. After TRAIL engagement, DR4 (TRAIL-R1), through activation of NF-κB, induces apoptosis in the TRAIL ligated cell. |
Immunogen | Extracellular domain of DR4-human IgG1 Fc fusion protein |
Other Names | TRAIL-R1, Apo-2, CD261, TNFRSF10A |
Gene, Accession # | Gene ID: 8797 |
Catalog # | 307211 |
Price | $369 |
Order / More Info | Human CD261 (DR4, TRAIL-R1) Antibody from BIOLEGEND |
Product Specific References | n/a |