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Antigenic Specificity | Mouse CD223 (LAG-3) |
Clone | C9B7W |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG1, κ |
Format | Brilliant Violet 650™ conjugate |
Size | 50 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Brilliant Violet 650™ anti-mouse CD223 (LAG-3). CD223, also known as LAG-3, is 70 kD type I transmembrane glycoprotein within the Ig superfamily. It is the gene product of lymphocyte activation gene-3 (Lag3) with structural similarity to CD4. CD223 is expressed on activated T cells and NK cells, as well as T regulatory cells. CD223, like CD4, binds MHC class II molecules, but with higher affinity than CD4. In association with the CD3 complex, CD223 has been shown as a negative regulatory molecule to inhibit TCR-mediated signaling and regulate |
Immunogen | Murine CD223-Ig fusion protein |
Other Names | LAG3, LAG-3 |
Gene, Accession # | Gene ID: 16768 |
Catalog # | 125227 |
Price | $297 |
Order / More Info | Mouse CD223 (LAG-3) Antibody from BIOLEGEND |
Product Specific References | PubMed: 30699352, 31433988, 31924474, 32923626, 33007259, 33979613, 34010637 |