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Antigenic Specificity | ZAP70 Phospho (Tyr319)/Syk Phospho (Tyr352) |
Clone | 1503310 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | Alexa Fluor® 594 conjugate |
Size | 25 µg |
Concentration | n/a |
Applications | ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Alexa Fluor® 594 anti-ZAP70 Phospho (Tyr319)/Syk Phospho (Tyr352). ZAP70 was identified in TCR-stimulated Jurkat cells. It is an inactive cytosolic tyrosine kinase that is recruited to a transmembrane receptor lacking intrinsic catalytic activity. ZAP70 and the related spleen tyrosine kinase (Syk) play a critical role in T-cell development and activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family ki |
Immunogen | Modified peptide. |
Other Names | Phospho Zeta-Chain (TCR) Associated Protein Kinase 70 kD, Phospho SRK, Phospho 70 KD Zeta-Chain Associated Protein, Phospho Tyrosine-protein kinase ZAP-70 |
Gene, Accession # | Gene ID: 7535 |
Catalog # | 683713 |
Price | $180 |
Order / More Info | ZAP70 Phospho (Tyr319)/Syk Phospho (Tyr352) Antibody from BIOLEGEND |
Product Specific References | n/a |