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Antigenic Specificity | Mouse B7-H4 (B7S1, B7X) |
Clone | HMH4-5G1 |
Host Species | Armenian Hamster |
Reactive Species | mouse |
Isotype | IgG |
Format | purified, low endotoxin, azide-free |
Size | 1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Ultra-LEAF™ Purified anti-mouse B7-H4 (B7S1, B7X). B7-H4 is a newly discovered B7 family member that negatively regulates T cell immunity. In vitro, B7-H4 inhibits CD4 and CD8 T cell proliferation, cytokine production, and generation of alloreactive cytotoxic T-cells (CTLs). In vivo, blockage of endogenous B7-H4 by specific monoclonal antibodies promotes T cell responses. A new reported function of B7-H4 is as an important negative regulator of innate immunity through growth inhibition of neutrophils. It has been reported that B7-H4 is not con |
Immunogen | Mouse B7-H4 human IgG1 Fc fusion protein |
Other Names | B7H4, B7S1, B7-S1, B7x |
Gene, Accession # | Gene ID: 242122 |
Catalog # | 139410 |
Price | $677 |
Order / More Info | Mouse B7-H4 (B7S1, B7X) Antibody from BIOLEGEND |
Product Specific References | n/a |