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Antigenic Specificity | Mouse CD253 (TRAIL) |
Clone | N2B2 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a, κ |
Format | TotalSeq™-B oligomer conjugate |
Size | 10 µg |
Concentration | n/a |
Applications | PG |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TotalSeq™-B0925 anti-mouse CD253 (TRAIL). CD253 is a 40 kD TNF superfamily member known as TRAIL, Apo-2 ligand, and Apo-2L. TRAIL is expressed on a variety of cells, including IL-2 and IL-15 activated NK cells and activated T cells. However, it is undetectable on resting T and B cells. TRAIL has been reported to induce apoptosis in tumor and transformed cell lines by a caspase-dependent process. The N2B2 antibody has been reported to be useful for flow cytometric staining and blocking NK cell cytotoxicity in vitro. |
Immunogen | Mouse TRAIL-transfected 2PK-3 cells |
Other Names | TNFSF10, TNF-related apoptosis inducing ligand, Apo-2 ligand, Apo-2L, CD253 |
Gene, Accession # | Gene ID: 22035 |
Catalog # | 109321 |
Price | $369 |
Order / More Info | Mouse CD253 (TRAIL) Antibody from BIOLEGEND |
Product Specific References | n/a |