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Antigenic Specificity | FUS |
Clone | 10F7 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1, κ |
Format | purified |
Size | 25 µg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-FUS. FUS/TLS is an RNA-binding protein that was originally discovered as a fusion protein caused by chromosomal translocation in cancer. FUS/TLS is as an important member of the cellular DNA repair response. The C-terminal end of FUS is involved in protein and RNA binding, while the N-terminal motif of FUS plays a role in transcriptional activation. FUS was also shown to accumulate in the cytoplasm of neurons under hyperosmotic conditions, and FUS mislocalization has been implicated as being the firs |
Immunogen | Human TLS/FUS recombinant protein fused with GST tag. |
Other Names | FUS, TLS |
Gene, Accession # | Gene ID: 2521, 233908, 217385 |
Catalog # | 855001 |
Price | $106 |
Order / More Info | FUS Antibody from BIOLEGEND |
Product Specific References | n/a |