Presenilin 2 Antibody from BIOLEGEND

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Antigenic SpecificityPresenilin 2
ClonePS2
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1, κ
Formatpurified
Size100 µg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionPurified anti-Presenilin 2. Mutations in the genes for presenilin 1 (PS1) and 2 (PS2) are the causative factors for about 50% of early onset familial Alzheimer?s disease. PS1 and PS2 are homologous transmembrane proteins, and along with nicastrin, form high molecular mass multimeric protein complexes involved in the intramembranous proteolysis of several proteins including amyloid precursor protein (APP) and Notch receptors. Absence of PS1 is associated with dramatic reductions in the levels of mature glycosylated nicastri
ImmunogenThis monoclonal antibody was raised using a GST-fusion containing the complete N-terminal fragment of human Presenilin 2 (residues 1-87).
Other NamesPresenilin-2, AD5, E5-1, PS-2, AD3LP, STM-2, gamma-secretase, PSEN2, PS2
Gene, Accession #Gene ID: 5664
Catalog #814204
Price$276
Order / More InfoPresenilin 2 Antibody from BIOLEGEND
Product Specific Referencesn/a
BIOLEGEND
BIOLEGEND
BIOLEGEND
8999 BioLegend Way
San Diego CA 92121
P: (858) 455-9588
P: 1-877-Bio-Legend (246-5343)
F: (858) 455-9587

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