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Antigenic Specificity | PARP |
Clone | 5A5 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | purified |
Size | 25 µg |
Concentration | n/a |
Applications | Western Blot (WB), KO/KD-Western Blot (WB), ICC, IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-PARP. PARP (Poly (ADP-ribose) polymerase) is a 113 kD nuclear protein that can exist as a homo- or hetero-dimer. This protein acts as a molecular ?nick sensor? and functions in base excision repair, poly(ADP-ribosyl)ation of acceptor proteins involved in chromatin architecture and DNA metabolism and participates in protein modification to enhance or repress transcription. PARP is ribosylated by PARP2 and is a target for caspase cleavage during apoptosis. PARP interacts with proteins in the base excisi |
Immunogen | Recombinant (partial), N-terminal 2/3 sequence of PARP |
Other Names | Poly (ADP-ribose) polymerase |
Gene, Accession # | Gene ID: 142 |
Catalog # | 614301 |
Price | $101 |
Order / More Info | PARP Antibody from BIOLEGEND |
Product Specific References | PubMed: 22664159, 24047976, 27918308, 32582999 |