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Antigenic Specificity | Parvalbumin |
Clone | A17130G |
Host Species | Mouse |
Reactive Species | mouse |
Isotype | IgG2b, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-Parvalbumin. Parvalbumin is a calcium-binding protein with diverse functions in various tissues. Originally identified in skeletal muscle fibers, parvalbumin holds particular significance in the central nervous system. In neurons, parvalbumin acts as a calcium buffer, helping to maintain precise control over calcium ion levels within the cell. This function is critical for regulating synaptic transmission, especially at inhibitory synapses where it influences the release of the neurotransmitter GABA to synchronize the activity of neural networks. Additionally, parvalbumin contributes to the plasticity of synaptic connections, affecting learning and memory. Overall, parvalbumin's multifaceted role underscores its importance in shaping the intricate dynamics of the nervous system and maintaining its proper functioning. |
Immunogen | Recombinant N-terminus fragment of human parvalbumin |
Other Names | Parvalbumin alpha (PVALB), D22S749 |
Gene, Accession # | Gene ID: 5816 |
Catalog # | 626152 |
Price | $405 |
Order / More Info | Parvalbumin Antibody from BIOLEGEND |
Product Specific References | n/a |