Mouse CD317 (BST2, PDCA-1) Antibody from BIOLEGEND
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| Antigenic Specificity | Mouse CD317 (BST2, PDCA-1) |
| Clone | 927 |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2b, kappa |
| Format | Spark PLUS UV395™ conjugate |
| Size | 25 µg |
| Concentration | n/a |
| Applications | FC - Quality tested |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Spark PLUS UV395™ anti-mouse CD317 (BST2, PDCA-1). CD317, known as BST2, tetherin, HM1.2 antigen, bone marrow stromal antigen 2, or PDCA-1, is type II transmembrane glycoprotein with a molecular mass of 29-33 kD. It is predominantly expressed on Type I IFN-producing cells (IPCs) in naïve mice, but is up-regulated on most cell types following stimulation with type I IFNs and IFN-gamma. It is highly expressed on terminally differentiated normal plasmacytoid dendritic cells and some tumor cells, such as multiple myeloma, renal cell carcinoma, and melanoma cells. BST2 is a recently identified, IFN-induced cellular response factor that blocks release of HIV-1 and other retroviruses from infected cells. BST2 has been found to be the natural ligand of ILT7 in human model. |
| Immunogen | Mouse plasmacytoid dendritic cells (DCs) |
| Other Names | BST2, tetherin, HM1.2 antigen, bone marrow stromal antigen 2, PDCA-1 |
| Gene, Accession # | Gene ID: 69550 |
| Catalog # | 127047 |
| Price | $170 |
| Order / More Info | Mouse CD317 (BST2, PDCA-1) Antibody from BIOLEGEND |
| Product Specific References | n/a |
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