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Antigenic Specificity | β-Amyloid Pyroglutamyl (Glu3) |
Clone | 337.48 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | purified, azide-free |
Size | 100 µL |
Concentration | n/a |
Applications | IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified (azide-free) anti-β-Amyloid Pyroglutamyl (Glu3). Amyloid beta (Aβ or Amyloid beta) denotes peptides of 36-43 amino acids in length that are crucially involved in Alzheimer?s disease as the main component of the amyloid plaques found in the brains of Alzheimer patients. The peptides result from the amyloid precursor protein (APP), which is cut by certain enzymes to yield Aβ. Aβ molecules can aggregate to form oligomers (known as ?seeds?) which are believed to be able to induce other Aβ molecules to also take the misfolded oligomeric form, leadi |
Immunogen | This monoclonal antibody was raised against a synthetic peptide corresponding to amino acids 3 through 16 of Amyloid Beta with a pyroglutamyl post translational modification at the third glutamate position (E3). |
Other Names | Amyloid beta A4 protein, preA4, protease nexin-II, peptidase nexin-II, beta-amyloid peptide, APP, Amyloid Precursor Protein, Pyroglutamate-modified Aβ, Pyroglutamate amyloid-β (Aβ), PyroGlu- Aβ, PyroGlu Abeta, Pyroglutamate-3 Amyloid-β |
Gene, Accession # | Gene ID: 351 |
Catalog # | 822301 |
Price | $275 |
Order / More Info | β-Amyloid Pyroglutamyl (Glu3) Antibody from BIOLEGEND |
Product Specific References | n/a |