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Antigenic Specificity | Mouse CD152 |
Clone | UC10-4B9 |
Host Species | Armenian Hamster |
Reactive Species | mouse |
Isotype | IgG |
Format | PE-Cyanine5 conjugate |
Size | 25 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PE/Cyanine5 anti-mouse CD152. CD152, also known as CTLA-4 or Ly-56, is a 33 kD member of the immunoglobulin superfamily. It is expressed on activated T and B lymphocytes. CD152 is similar to CD28 in amino acid sequence, structure, and genomic organization and these two receptors share common B7 family counter-receptors (B7-1, B7-2). Whereas CD28 delivers a costimulatory signal in T cell activation, CTLA-4 negatively regulates cell-mediated immune responses. CD152 is thought to play a role in the induction and maintenance of immunological tolerance as well as the development of protective immunity and thymocyte regulation. |
Immunogen | Mouse CTLA-4-mouse IgG2a fusion protein |
Other Names | Cytotoxic T Lymphocyte-Associated Antigen-4 (CTLA-4), Ly-56 |
Gene, Accession # | Gene ID: 12477 |
Catalog # | 106337 |
Price | $147 |
Order / More Info | Mouse CD152 Antibody from BIOLEGEND |
Product Specific References | n/a |