Edit |   |
---|---|
Antigenic Specificity | Syk |
Clone | SYK-01 |
Host Species | Mouse |
Reactive Species | human, rat, mouse |
Isotype | IgG1, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB), IHC-P, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-Syk. Syk is a cytoplasmic 72 kD non-receptor tyrosine kinase that is widely expressed in hematopoietic cells. The Syk kinase associates with a number of proteins including c-Src, Lck, Lyn, Fyn, Vav1, STAT3, SHP1, Grb2, and LAT to couple immunoreceptors to downstream signaling events mediating cellular proliferation, differentiation, and phagocytosis. Syk is modified by phosphorylation on multiple tyrosine sites. The SYK-01 monoclonal antibody (raised against amino acids 5-360 of human Syk) recognizes |
Immunogen | Partial recombinant (amino acids 5-360) human Syk |
Other Names | Spleen tyrosine kinase, protein tyrosine kinase SYK |
Gene, Accession # | Gene ID: 6850 |
Catalog # | 626202 |
Price | $293 |
Order / More Info | Syk Antibody from BIOLEGEND |
Product Specific References | PubMed: 21135164, 21354221, 22854286, 24899508, 26157172, 27758892, 31825964 |