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Antigenic Specificity | PPARγ |
Clone | 14G4B17 |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB), ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-PPARγ. PPARγ, also known as NR1C3, is a ligand-dependent transcription factor belonging to the peroxisome-proliferator activated receptor (PPAR) family. Upon activation by its ligands, such as fatty acids and prostaglandin PGJ2, PPARγ forms heterodimers with the retinoid X receptors (RXRs) and binds to DNA specific PPAR response elements (PPRE). In the absence of ligand, the PPARγ/RXR heterodimer represses its target genes by recruiting and stabilizing the corepressor complexes at the promoter regions. |
Immunogen | Synthetic PPARγ peptide conjugated to KLH (CETDMSLHPLLQEIYKDLY) |
Other Names | Peroxisome proliferator-activated receptor gamma, PPAR gamma, NR1C3 |
Gene, Accession # | Gene ID: 5468 |
Catalog # | 683402 |
Price | $288 |
Order / More Info | PPARγ Antibody from BIOLEGEND |
Product Specific References | PubMed: 33521697 |