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Antigenic Specificity | Notch 1 |
Clone | mN1A |
Host Species | Mouse |
Reactive Species | mouse, human |
Isotype | IgG1, κ |
Format | phycoerythrin (PE) conjugate |
Size | 100 µg |
Concentration | n/a |
Applications | Intracellular Staining for Flow Cytometry (ICFC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PE anti-Notch 1. Notch1, also known as neurogenic locus notch homolog protein 1, is a large >270 kD protein that functions as a receptor for the membrane ligands Jagged1, Jagged2 and Delta1 to regulate cell fate decisions. Upon ligand activation, the transmembrane Notch1 receptor is cleaved by TNF-alpha converting enzyme (TACE) to produce a membrane-associated intermediate fragment (NEXT). This fragment is further cleaved by presenilin-dependent gamma secretase to release a notch-derived peptide containing the i |
Immunogen | Notch1 GST fusion protein |
Other Names | Neurogenic locus notch homolog protein 1, Notch-1 |
Gene, Accession # | Gene ID: 4851 |
Catalog # | 629106 |
Price | $202 |
Order / More Info | Notch 1 Antibody from BIOLEGEND |
Product Specific References | PubMed: 26766040, 28112644 |